I’ve used Google Reader for years. I find it a really useful way of managing the many RSS feeds I subscribe to, but I hate its online interface. This means that I’ve spent years using various desktop applications that work with it. I’ve tried lots of them, but the one that’s currently occupying a space on my dock is Reeder, which I also use on my iPhone.
Reeder has everything I want in an RSS reader. It allows me to manage my Google Reader subscriptions from within the app, which many alternatives don’t. It clearly shows my entire RSS inbox on the left, and the contents of each individual item on the right. The weblink to the full article is a click away, as is the Readability version, which I usually try first. It will allow me to tweet or email articles with a single click, and also has a button to send them straight to Pocket. There are built-in options for loads of other services too.
I think Reeder is brilliant, and I highly recommend it.